Which is better gaviscon or zantac

They have been shown to heal irritation of the tube between the throat and the stomach the esophagus. You can get relief from a less powerful drug. And when you do need a PPI, you should take the lowest dose for as short a time as possible.

More than half of the people who take PPIs probably do not need them. Simple heartburn can be treated with antacids or other drugs, plus diet and lifestyle changes. You may only have heartburn every now and then—such as after a big, spicy meal. This may be uncomfortable, but it is not serious. Talk to your doctor if you have indigestion, or heartburn and acid reflux. There are similar medicines they can prescribe for you if you need treatment.

If you've taken ranitidine in the past, any risk is likely to be very low, but if you have any concerns, speak to a pharmacist or doctor. The same primary outcome was used in a trial comparing rabeprazole vs.

Alginates showed proven efficacy against GERD symptoms in randomised trials vs. The limitation of the GOOD trial was the treatment period, which was only 14 days, with the primary outcome set during the first 7 days of treatment. As the primary outcome was the time to onset of the first h heartburn-free period, each day was divided into four periods so as to have four symptom assessments per day. As the treatment was symptomatic, this endpoint was relevant clinically and from the patient's point of view.

The comparison was between two drugs with different pharmacokinetic and pharmacodynamic properties. Alginates display immediate action, forming a raft floating over the stomach contents, eliminating or displacing the postprandial "acid pocket", so that, in case of reflux, the raft is regurgitated first into the lower oesophagus, reducing acid contact, especially when the subject is standing [ 16 — 21 ].

The raft may remain in the stomach for several hours [ 18 ] but is then evacuated, so that 3 or 4 doses per day are required for optimal efficacy. The trial used a simple, relevant and pragmatic primary clinical endpoint rather than a composite score such as symptom frequency plus intensity. In these patients, alginates and antacids were often restricted to self-medication.

This is a relevant and useful alternative and an effective non-systemic approach that should help reduce excessive use of curative or preventive prescriptions of PPIs [ 30 ]. PPIs are a well-tolerated pharmacologic class, but concomitant prescription of omeprazole with clopidogrel should be managed carefully after coronary stenting [ 31 — 33 ]. Some authors suggested that prolonged PPI therapy could increase Clostridium difficile infection [ 34 ], community-acquired pneumopathy [ 35 ] and risk of hip fracture [ 36 , 37 ], so that this pharmacologic class should be prescribed in moderation if other safe rapid-relief solutions are available.

Spechler SJ: Epidemiology and natural history of gastro-oesophageal reflux disease. PubMed Google Scholar. Presse Med. Article PubMed Google Scholar. Cochrane Database of Systematic Reviews. DOI: Book Google Scholar. Clin Gastroenterol Hepatol. Filoche B, Carteret E, Couzigou B, et al: Randomized double-blind trial with a liquid suspension of alginate for the treatment of pyrosis. Gastroenterol Clin Biol. A comparison of old and new medical management.

J Kans Med Soc. Curr Med Res Opin. Chatfield S: A Comparison of the efficacy of the alginate preparation, Gaviscon advance, with placebo in the treatment of gastro-oesophageal reflux disease.

Int J Pharm. Statist Med. Article Google Scholar. Miner P, Orr W, Filippone J, et al: Rabeprazole in non-erosive gastroesophageal reflux disease: a randomized placebo-controlled trial. Am J Gastroenterol.

Monnikes H, Pfaffenberger B, Gatz G, et al: Novel measurement of rapid treatment success with ReQuest: first and sustained symptom relief as outcome parameters in patients with endoscopy-negative GERD receiving 20 mg pantoprazole or 20 mg esomeprazole.

Curr Gastroenterol Rep. Comparison with equal-strength antacid. Dig Dis Sci. Aliment Pharmacol Ther. Armstrong D, Talley NJ, Lauritsen K, et al: The role of acid suppression in patients with endoscopy-negative reflux disease: the effect of treatment with esomeprazole or omeprazole.

Multicenter Study. An evidence-based appraisal of reflux disease management--the Genval Workshop Report. Gaviscon , create a foam barrier on top of the stomach contents and protect the esophagus from contact with gastric acid. These antacids relieve both acid reflux and sour stomach by temporarily neutralizing the gastric acid already produced in the stomach. They are generally formulated with one or more of the following salts: calcium, aluminum or magnesium.

Antacids that contain only calcium Antacids that contain only calcium carbonate e. Tums provide effective short-term relief. Antacids that contain both aluminum and magnesium e.

Diovol Plus have the advantage of providing rapid relief of sour stomach and acid reflux by neutralizing gastric acid. Acid neutralizers generally work from 2 to 4 hours, depending on the person and the amount of gastric acid produced. H2 antagonists, such as ranitidine Zantac and famotidine Pepcid act directly on the cells of the stomach to reduce the quantity of acid produced and are effective for both sour stomach and acid reflux.

H2 antagonists start to work after about one hour. Proton-pump inhibitors such as omeprazole and esomeprazole work by decreasing the amount of acid produced by the stomach for a long-lasting relief of heartburn.

They may be suitable for you if you experience gastric symptoms more than twice a week and if antacids do not relieve you. Ask your pharmacist if this product is right for you.